(Senior / Principal) Scientist, Immunology (职位编号：20585925)社

面议

市辖区博士及以上2年及以上

发布时间：2023-09-06

职位描述

Primary Purpose of JobCollaborate with a group of immunology/oncology scientists and associates to provide expert biology support to preclinical and clinical studies for the discovery and development of new therapeutic agents (small molecule compounds). Scientists are responsible for contributing to new medical hypothesis, new target validation, new project initiation and progression, and drafting and execution of research plans for nominating new projects. Commensurate with experience, scientists expected to lead cross-functional discovery project team(s) and/or support projects with biology expertise. Apply skills in drug discovery to assess the potency, selectivity, safety, PK and PD of novel molecules. Scientists will apply advanced genetic tools e.g., CRISPR/Cas9 for new target discovery, drug target validation and biomarker discovery.
Principle Roles & Responsibilities / Accountabilities
Drive or support target identifications in collaboration with translational medicine, disease biology research, and chemistry teams.
Initiate new drug discovery projects based on scientific insight with cross-functional input.
Design and implement various in vitro and in vivo studies to study potency, selectivity, and to elucidate molecular mechanism of drug action and efficacy based on scientific considerations within the context of team or project goals.
Perform scientific analysis for results interpretation and present them collaboratively.
Initiate and execute research activities related to identification and characterization of novel therapeutic targets and compounds.
Investigate and develop methods or technologies for the rapid advancement of projects.
Prepare standard operational protocols, study reports and high-quality manuscripts.
Other related duties as required, including but not limiting to organizing and maintaining laboratory and training associates and/or junior scientists.
Work in a flexible schedule to meet deadlines.
Qualification and ExperienceEducation/Qualifications
Ph.D. in immunology, cancer biology, molecular biology, nephrology, rheumatology or a related field. PhD with medical knowledge (MD) is a plus. Post-doctoral training experience is preferred. Industrial experience in drug discovery is a plus. Oversea education and/or training experience is preferred.
Leadership Competencies
Should communicate effectively, collaborate efficiently with co-workers (cross functions and/or sites), and be able to train junior level associates and/or scientists.
Job Required Competencies
Deep knowledge of immunology and/or cancer biology is required; Cancer biology or immunology is preferred.
Disease biology of the gut, kidneys and connective tissues is preferred.
Experience in genetics/genomics e.g., CRISPR/Cas9 genome editing is a plus.
Should be proficient in designing and conducting experiments involving the state of the art techniques within the areas of cancer biology, immunology, biochemistry, molecular biology, and pharmacology.
Be capable of understanding chemistry and DMPK results and collaborating effectively cross functions.
Recognize novelty of patentable ideas where applicable and contribute to patents.
Contribute to scientific publications.
Good communication in English and be capable of presenting results both inside and outside of company.
Have and maintain thorough knowledge of related scientific field and apply this knowledge to advance projects or programs.
Be able to record and present results in English, fluent Chinese is a plus.
Title of positions (Principal Associate, Scientist, and Senior Scientist) matched with candidate’s qualifications and years of experience.

其他要求

招聘人数：5人
职能类别：

公司介绍

上海罗氏制药有限公司成立于1994年，是抗肿瘤、抗**、移植等关键领域的市场领导者。在大型跨国药企中，我们率先在中国建成了包括研究、开发、生产、营销等环节在内的完整的医药价值产业链。罗氏中国正向着成为罗氏全球第三个战略中心的目标迈进，以实际行动践行在中国长期发展的承诺。

我们始终以患者为中心，致力于帮助患者从根本上延长生命和改善生活质量。目前，罗氏在华拥有16个产品，覆盖8个治疗领域。我们与**、医疗机构以及非**组织等社会各界多方携手，共同探索创新的合作模式，通过一系列有影响力和可持续的举措惠及更多的中国患者。

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