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生物主管,Director of Biology

30K-50K/月

深圳市博士及以上5年及以上30-45岁

发布时间:2019-01-25

五险一金 定期体检 节日福利 意外保险 带薪年假 员工培训

职位描述

岗位职责:
(1) Establish and manage kinase inhibitors in vitro screening platform; recruit, teach and develop biologists and pharmacologists with drug discovery experience.

(2) Design, develop and execute pre-clinical cellular, enzymatic and biological assays; identify final drug targets, final drug candidates and their optimization and the bioassays and pharmacology associated with above.

(3) Analyze and evaluate experimental data for clinical candidate selection.

(4) Track record and report pre-clinical biological activity research progress, find and resolve possible problems on a timely basis.

(5) Conduct high quality technical reports and summaries, strategic plan for different development stages, as well as regular report to the head of the company.

(6) Understand and stay abreast of intellectual property considerations in terms of research direction and final drug target and candidate selection.

(7) Oversee internal staff and Contract Research Organizations (CROs) to meet timelines.

任职资格:
(1) Ph.D. in Molecular Pharmacology, Molecular Biology, Cell Biology, Enzymology, Biochemistry, Pharmacology, or related discipline with 5+ years of experience in academia and industry with small molecule oncology drug discovery.

(2) Previous oversea pharmaceutical/biopharmaceutical industry experience in pre-clinical biological activity, pharmacological research, CRO management is strongly preferred.

(3) Ability to independently develop novel assays and cellular models for small molecule drug screening. Proficiency in standard biochemical, cellular and molecular techniques.

(4) Familiarity with the development of drug candidates from target identification, validation, discovery, pharmacological studies, to IND.

(5) Broad and deep understanding of signaling pathways and biological processes implicated in cancer and the mechanisms of action of targeted therapies and mechanisms of acquired resistance.

(6) In-depth understanding of basic in vitro drug screening, and efficacy and safety profile for anti-cancer targeted agents research.

(7) Extensive knowledge of small molecule drug screening assay technologies with hands-on experience developing and performing cellular and enzyme activity in vitro assays.

(8) Hands on experience with, and a broad understanding of, in vitro and in vivo research methods and models used for targeted therapy research and discovery in oncology.

其他要求

  • 1人
  • 研发部
  • CEO
  • 普通话、英语
  • 分子生物技术

公司介绍

深圳市塔吉瑞生物医药有限公司创建于2014年,是一家中美合资的高科技医药研发公司。公司以挽救病人生命为核心,以市场需求为导向,致力于国际前沿的靶向新药研究与开发,并力争成为世界领先的靶向新药研发基地,挑战癌症获得性耐药的重大医学难题,使癌症不再是威胁人类生命的头号杀手。

深圳市塔吉瑞生物医药有限公司

行业:
制药.生物
规模:
1-49人
性质:
中外合营(合资/合作)
网址:
http://tjrbiosciences.com/
地址:
广东省深圳市南山 科苑路15号科兴科学园A1-301

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